Pathogens causing acute disease and death Clipper or lasting immunity require specific spatial or temporal processes to persist in populations.Host traits, such as maternally-derived antibody (MDA) and seasonal birthing affect infection maintenance within populations.Our study objective is to understand how viral and host traits lead to population

In animals, reproductive performance typically improves over time early in life.Several ultimate and proximate mechanisms may contribute to such an age-related improvement and these mechanisms can act in a relative or in an absolute sense.Low performance of young individuals may be the consequence of a comparison or competition with older individua

Twist2 (Dermo1) has been shown to mediate the epithelial-mesenchymal transition (EMT) to promote tumor invasion and even metastasis.However, the involvement of EMT in breast cancer progression is highly debated, partially due to clinical observations showing that the majority of human breast carcinoma metastases express E-cadherin and maintain thei

Abstract Adenosine deaminases acting on RNA (ADARs) impact diverse cellular processes and pathological conditions, but their functions in early cell-fate specification remain less understood.To gain insights here, we began by charting time-course RNA editing profiles in LED Lighting human organs from fetal to adult stages.Next, we utilized hPSC dif

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